Advances in Decision Sciences (ADS)

A Critique of Recent Medical Research in JAMA on COVID-19

A Critique of Recent Medical Research in JAMA on COVID-19


A Critique of Recent Medical Research in JAMA on COVID-19



The world community has been changed irrevocably by the highly infectious and mutating SARS-CoV-2 virus that causes the COVID-19 disease. The necessary research output on COVID-19 has been revolutionary, especially in the medical and biomedical sciences, where the search for a vaccine is essential for the world to have a semblance of normality in the era of COVID-19. Much of the advanced research has been distributed in the leading medical journals, including the Journal of the American Medical Association (JAMA), where the latest medical research is distributed on a daily basis, and where comments can also be published. The purpose of this paper is to provide a critique of 110 interesting and highly topical research papers that have been published in JAMA, mostly within the past two months. The diverse topics include:treating influenza and COVID-19 simultaneously, dealing with a second wave of COVID-19 in Beijing, honesty is best for known and unknown GAWI and WIST, unreliability of asymptomatic COVID-19 testing outcomes for children, the effectiveness of flu vaccines, acute anxiety during COVID-19, MAID as an end of life option, longer-term effects of corticosteroids on the mortality of critically ill COVID-19 patients, isolation, loneliness and psychological distress during COVID-19, the selection of volunteers for COVID-19 vaccine trials, the mental health of children and adolescents during COVID-19, fertility preservation through hormonal intervention for transgender adolescents, safe, effective and affordable COVID-19 vaccines, essential requirements for acceptance of a COVID-19 vaccine, ischemic stroke rates from COVID-19 and influenza, mandatory COVID-19 vaccination of children, COVID-19 asymptomatic children and adults, Who Dares Wins (Qui Audet Adipiscitur), even against COVID-19, global health security index and responses to COVID-19, quality of life and dying, immunity from COVID-19, whom to trust or not to trust regarding COVID-19, the value of health care for cancer patients, previous medical research bodes well for a COVID-19 vaccine, you cannot fight COVID-19 alone, causality between hypertension and COVID-19, coffee consumption and metastatic colorectal cancer, improving statistical analysis of health policies on children and adolescents, COVID-19 does not respect anyone, politics diminishes the integrity and reputation of healthcare agencies, primary, secondary and tertiary cancers in the lung, health care should include everyone, especially for COVID-19, prioritizing access to COVID-19 vaccines, further questions about COVID-19 vaccines, estimating direct and indirect excess deaths from COVID-19, herd immunity for COVID-19, daily eyeglass wear and COVID-19 infection, using anything that prevents the spread of COVID-19, deferral of care for serious non-COVID-19 conditions, society’s united fight against depression and suicide, the positive outcomes in delaying low-risk thyroid cancer treatment during COVID-19, the likely future toll from COVID-19, excluding older persons from vaccine and clinical trials for COVID-19, peaceful miracles make the moment, dealing with COVID-19 science denial and conspiracy theories, masking and testing should be mandatory for COVID-19, journal reputation is established by scientific creativity and destroyed by political interference, impact and importance of medical research on COVID-19, support for COVID-19 long haulers, possible reinfection and long term recovery from COVID-19, Wabi-Sabi and the beauty of imperfection, good, better and best testing for COVID-19, surgical technical skill and long-term cancer survival, prior negative recovery from RT-PCR test results for COVID-19, age, frailty, and postoperative surgical outcomes, all journals should have diversity in the editorial and peer review process, an encompassing digital open access journal – JAMA Health Forum, righting inequities through otolaryngology in a COVID-19 normal America, resilient mental health in older adults under COVID-19, preventing suicides in a COVID-19 normal world, and COVID-19, voluntary participation in cancer clinical trials, herd immunity and COVID-19, psychological distress of US adults under COVID-19, repurposing drugs for COVID-19, same data + different models = different results, how do surges in COVID-19 affect healthcare spending?, causality between sedentary behavior and cancer mortality, overdose cardiac arrests and emergency medicine during COVID-19, COVID-19 asymptomatic children versus adults, why is care for serious non-COVID-19 conditions seemingly deferred?, confidentiality in a world of COVID-19 and fake news, mental healthcare data disrupted by COVID-19, do N95 face masks protect against COVID-19?, the necessity of face masks during COVID-19, nurses in COVID-19 vaccine trials, eye protection for COVID-19 ventilated patients, and healthcare access, social needs, unemployment insurance during COVID-19, pre-eminent experts evaluate the distribution of COVID-19 vaccines, the effects of current vaccines against SARS-CoV-2 and COVID-19 mutations, unbearable suffering needs to be respected, varied public attitudes toward COVID-19 vaccine mandates, enanthems, exanthems, and COVID-19, a wish list for a COVID-19 new year, critical statistical rigour before and during COVID-19, accepting vaccines is essential against COVID-19, and social distancing, health behaviour, cancer outcomes during COVID-19, readmission and death from COVID-19 after hospital discharge, beneficial lessons from COVID-19, estimating racial disparities in COVID-19 testing, paying people to be vaccinated against COVID-19, COVID-19 mutations and vaccines, mandatory vaccinations against COVID-19, allergic reactions to the first dose of the Pfizer vaccine, neutralization of monoclonal antibodies for COVID-19, pricing teledermatology during COVID-19, and SARS-CoV-2 COVID-19 are spreading virtually everywhere, transmission of SARS-CoV-2 and COVID-19 by children, addressing racial and ethnic health disparities during COVID-19, race and medical research during and after COVID-19, adherence to nonpharmaceutical interventions during COVID-19, further unanswered questions for cancer patients during COVID-19, how are children affected by COVID-19, is the California variant another COVID-19 escaped mutant?, tracking escaped mutants of SARS-CoV-2 and COVID-19, optimal timing separation and strength of prime and booster shots, confounding errors in response to COVID-19, durability and duration of approved vaccines against escaped mutants, and hospital mortality and hospice discharge of COVID-19 patients depend on population size.


COVID-19, risk, influenza, asymptomatic, acute anxiety, corticosteroids, mortality, isolation, loneliness, psychological distress, vaccine trials, mental health, ischemic strokes, global health security index, quality of life and dying, hypertension, herd immunity, depression and suicide, science denial, conspiracy theories, masking, long haulers, reinfection, otolaryngology, herd immunity, psychological distress, sedentary behavior, cancer, cardiac arrests, fake news.


G32, H55, I12, I13, I18



A Critique of Recent Medical Research in JAMA on COVID-19 *
McAleer, Michael.
Advances in Decision Sciences ; 25(1):1-102, 2021.
Article in English | WHO COVID | ID: covidwho-1122538

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